Team 3 – STAFF – ALUMNI

“Welcome to Early stages of Parkinson’s disease”

MAP2/TGN-46/DAPI

Primary cortical neuron with staining for MAP2, TGN-46 and DAPI.

PPP2CA LRRK2

Primary cortical neuron with staining for PPP2CA and LRRK2.

CRISPR/Cas9

CRISPR/Cas9 technology used in the lab to silence or activate transcription in human cells: dCas9-mediated transcriptional modulation of phosphatases.
(A) dCas9 fused to effector domains can serve as an RNA-guided DNA-binding protein to target any protein to any DNA sequence. The effectors used with the catalytically inactive Cas9 (dCas9) are KRAB fusion protein to repress (CRISPRi) or the VP64 fusion protein to activate (CRISPRa) expression has shown on the picture.
(B) Stable suppression and overexpression of PPP1R1B by dCas9-KRAB or dCas9-VP64 in SH-SY5Y cells respectively. Cells stably expressing dCas9-KRAB or VP64 were infected with lentivirus constructs expressing a negative control sgRNA or two different sgRNAs targeting PPP1R1B.

Équipe Étapes précoces dans la maladie de Parkinson
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EARLY STAGES OF PARKINSON'S DISEASE

STAFF - ALUMNI

DEBROUCKER Amélie, PhD
EMANUELE Marco, PhD
LEPRETRE Frédéric, PhD
LARVOR Lydie, PhD

NKILIZA Aurore, PhD
GLORIAN SCHMITT Valérie, PhD
STIEVENARD Aliçia, PhD
TREVOR Tyson, PhD

VILTART Odile, PhD
WOLKOFF Nathalie, PhD

TRAINEESHIP
(Foreign researcher, Masters, Erasmus, Engineer, Technician, etc.)

ASSIBA Fatou, BTS
BAUDELEY Claire-Aline, Licence 3
BEEKHAREE Diana, Master 2
BONTE Marie-Amandine, Master 1
BOUGEOIS Paul, Master 2 Santé
CATSBURT Lisa, Master Erasmus, Nederland
DANENS Matthieu, DU- ITB

DIOP Fatou-Yali, Licence 3
FERNANDEZ LOPEZ Belén, Post-doctorant FEBS Fellowship, Spain
HOPES Lucie, M2 R, Thèse de médecine
LARA ORDONEZ Antonio Jesus, Master Erasmus, Spain.
LESUR Blandine, Licence 3
LEFEBVRE Jonathan, BTS
LEFEBVRE Réginald, IUT, Licence

LORGNIER Timothée, Master
MANIEZ Sophie, Licence 2 et 3, Master 2
PENET Justine, Master 1
PHAN Cécile, Master 2
SAITOSKI Kevin, Master 2
VAN LANDEGEM Antoine, Master 1
VERIN Justine, Master 2